Recombinant Mouse IL7
Cat. No.
Z200645
Unit
10 µg
Price
$205.00
Specifications
| Description | IL7 is a hematopoietic growth factor constitutively produced by stromal cells from the bone marrow and thymus. It is critical for B and T cell development and survival. IL7 promotes the differentiation of hematopoietic stem cells to lymphoid precursor cells by binding to a receptor composed of common gamma chain and IL-7Ra (CD127). Lymphoid precursor cells give rise to T cells, B cells, and natural killer cells. Furthermore, IL7 provides signals to regulate the survival of naive and memory CD4+ and CD8+ T cells NK T cells, innate lymphoid cells, and T regulatory cells. During B-cell development, IL7 also provides signals to promote survival, proliferation and differentiation. Recombinant mouse IL7 is a non-glycosylated protein with a molecular mass of 15.2 kDa. |
| SKU | Z200645 |
| Unit quantity | 10 µg |
| Family | Other Interleukins |
| Aliases | Interleukin-7 |
| Gene Symbol | IL7 |
| Gene ID | 16196 |
| Source | E. coli |
| Species | Mouse (M. musculus) |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 µm filtered solution in PBS and 2% trehalose, pH 7.4 |
| Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
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