Recombinant Mouse IL25 (E. coli)
Specifications
Description | IL-25 (also known as IL- 17E), a member of the IL-17 family, has been implicated in Th2 cell-mediated immunity. Recently, IL-25 has been identified as one of the initiators of the Th2 response (10, 11) and has also been shown to be expressed by mast cells. The transgenic overexpression of IL-25 by lung epithelial cells results in mucus hyperproduction and airway infiltration of macrophages and eosinophils; conversely, IL-25 blockade reduced airway inflammation and Th2 cytokine production in an allergen-induced asthma model. |
SKU | Z200255 |
Unit quantity | 10 µg |
Family | IL-17 Family |
Aliases |
UPF0556 protein, IL-25, Stromal cell-derived growth factor SF20, D17Wsu104e, Il25 Recombinant Mouse Interleukin-25 (IL25) |
Gene Symbol | IL25 |
Gene ID | 140806 |
Accession Number | Q9CPT4 |
Source | E. coli |
Species | Mouse (M. musculus) |
Appearance | Lyophilized Powder |
Molecular Weight | 16 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from 0.2μm filtered solution in Tris and NaCl |
Function | The ED(50) was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was found to be <0.5ng/mL. |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
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