Recombinant Human VEGFB (E. coli)
Specifications
Description |
Vascular endothelial growth factor B (VEGFB) is a homodimeric, heparin-binding glycoprotein member of the VEGF family of growth factors. Compared to VEGFA, VEGFB’s main role is the maintenance of newly formed blood vessels and is involved in endothelial cell physiology. It is a ligand for vascular endothelial growth factor receptor 1 (VEGFR1) and neuropilin-1 (NRP1). VEGFB (amino acids 22-207) is fused to a His tag that adds 21 amino acids to the N-terminus. |
SKU | Z102535 |
Unit quantity | 25 µg |
Family | VEGF/PGDF/Pleiotrophin Family |
Aliases |
VEGF-related factor |
Gene Symbol | VEGFB |
Gene ID | 7423 |
Accession Number | P49765 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 19 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | 0.2 µm filtered solution in 20 mM Tris-HCl buffer pH 7.5 and 10% glycerol |
Function | Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml. |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage, we recommend adding a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
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