Recombinant Human Thymosin-Beta 4 (TMSB4X) (E. coli)
Specifications
Description | The primary function of the T beta-4 member of the Thymosin-beta family is to maintain the organization of the cell’s cytoskeletal structure. Produced by myoblasts and fibroblasts, TMSB4X acts as a modulator for the production and digestion of actin and to inhibit filamentous actin polymerization. TMSB4X has also been found to induce phenotypic changes in T cell lines during early host defence mechanisms and inhibit the progression of hematopoietic pluripotent stem cells into the s-phase. |
SKU | Z102005 |
Unit quantity | 20 µg |
Family | Other Growth Factors/Cytokines |
Aliases | T beta-4, Hematopoietic system regulatory peptide, Seraspenide, TMSB4X, TB4X, TMSB4 |
Gene Symbol | TMSB4X |
Gene ID | 7114 |
Accession Number | P62328 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 5.2 kDa |
Endotoxin Level | < 1.0 EU/µg of recombinant protein as determined by the LAL method. |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS |
Function | The ED(50) was determined by the dose-dependent proliferation of immortalized mouse brain endothelial cells and was found to be <0.5ng/mL. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
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