Recombinant Human MCP-4 (CCL13) (E. coli)
Cat. No.
Z100645
Unit
Price
$89.00
Specifications
| Description | Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils, monocytes, and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells, and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis. The expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy. The recombinant construct corresponds to the “short-chain” of CCL13 spanning amino acids 24 – 98. |
| SKU | Z100645 |
| Unit quantity | 25 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases |
Monocyte chemotactic protein 4, CCL13, NCC-1, C-C motif chemokine 13, Small-inducible cytokine A13, MCP4, NCC1, SCYA13 Recombinant Human Monocyte Chemoattractant Protein-4 (CCL13) |
| Gene Symbol | CCL13 |
| Gene ID | 6357 |
| Accession Number | Q99616 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 9 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PB, 100mM NaCl, pH 7.5 |
| Function | Determined by its ability to chemoattract human monocytes using a concentration range of 20-40 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
STR
There are no STR for this product yet!
FAQs
There are no FAQs for this product yet!
References
There are no references for this product yet!
Controls and Related Product:
Other Cell Lines
Select Species:
African Green Monkey (C. aethiops)
(0)
Bat
(0)
Bat (Chiroptera)
(0)
Bee
(0)
Bottlenose Dolphin (Tursiops)
(0)
Cabbage Looper (T. ni)
(0)
Cat (Feline)
(0)
Cattle
(0)
Chicken (Galline)
(0)
Chinese Hamster (C. griseus)
(0)
Cow (Bovine)
(0)
Deer (Cervidae)
(0)
Dog (Canine)
(0)
Duck (Anas)
(0)
Duck (Anatidae)
(0)
E. coli
(0)
European Sea Bass
(0)
European Sea Bass (D. labrax)
(0)
Fall Armyworm (S. frugiperda)
(0)
Fish
(0)
Fly (D. melanogaster)
(0)
Frog (Xenopus)
(0)
Fruit Fly (D. melanogaster)
(0)
Gilthead Sea Bream (S. aurata)
(0)
Goat (Capra)
(0)
Golden Hamster (M. auratus)
(0)
Goose (Anatidae)
(0)
Green Monkey (C. aethiops)
(0)
Green Monkey (C. sabaeus)
(0)
Hamster (M. auratus)
(0)
Horse (Equine)
(0)
Human
(0)
Human (H. sapiens)
(0)
Insect
(0)
Insect (Insecta)
(0)
Killifish (F. heteroclitus)
(0)
Luciola italica
(0)
Marmoset (Primate)
(0)
Mink
(0)
Mink (N. vison)
(0)
Monkey (Primate)
(0)
Moth (S. frugiperda)
(0)
Mouse
(0)
Mouse (M. musculus)
(0)
N/A
(0)
Other
(0)
Photinus pyralis
(0)
Pig (Porcine)
(0)
Quail (Coturnix)
(0)
Rabbit (Leporidae)
(0)
Rabbit (Leporine)
(0)
Rainbow Trout (O. mykiss)
(0)
Rat (R. norvegicus)
(0)
Rat (Rattus)
(0)
Renilla reniformis
(0)
Roundworm (C. elegans)
(0)
Rous Sarcoma Virus (RSV)
(0)
SARS-CoV-2
(0)
Sheep (Ovine)
(0)
Sheep (Ovis)
(0)
Turtle
(0)
Turtle (Testudines)
(0)
Universal
(0)
Zebrafish (D. rerio)
(0)
Select Tissue:
0
(0)
Achilles Tendon
(0)
Adipose
(0)
Adrenal Gland
(0)
Adrenal Glands
(0)
Airway
(0)
Airway/Lung
(0)
Amniotic Sac
(0)
Antimesometrial Decidua
(0)
Antler
(0)
Ascites
(0)
Auditory
(0)
Bee Cell
(0)
Bile Duct
(0)
Bladder
(0)
Blood
(0)
Blood (Immune)
(0)
Blood Vessel
(0)
Bone
(0)
Bone Marrow
(0)
Brain
(0)
Breast
(0)
CAF, Tumor
(0)
Caput Epididymis
(0)
Cartilage
(0)
Cerebrospinal Fluid
(0)
Cervix
(0)
Colon
(0)
Connective Tissue
(0)
Cord Blood
(0)
Digestive
(0)
Digestive System
(0)
Ear
(0)
Embryo
(0)
embryonic
(0)
Endometria
(0)
Endometrium
(0)
Esophagus
(0)
Eye
(0)
Fallopian Tube
(0)
Fibroblast
(0)
Gingiva
(0)
Hair
(0)
Hair Follicle
(0)
Head/Neck
(0)
Heart
(0)
HeLa
(0)
Hepatocellular Carcinoma
(0)
Hippocampus
(0)
Intestinal
(0)
Intestine
(0)
Kidney
(0)
Kidney, Cortex/Proximal tubule
(0)
Labial Salivary Gland
(0)
Larynx
(0)
Liver
(0)
Lung
(0)
Lung Carcinoma
(0)
Lung, bronchus
(0)
Lymph
(0)
Lymph node
(0)
Lymphatic System
(0)
lymphoblast
(0)
Malignant melanoma
(0)
Mammary
(0)
Mesencephalic Tissue
(0)
Mesentery
(0)
Microglia
(0)
Mouth/Oral
(0)
Muscle
(0)
Myoblast
(0)
Nasal Mucosa
(0)
Nerve
(0)
Nervous System
(0)
Oesophageal
(0)
Oesophagus
(0)
Oral
(0)
Organ of Corti
(0)
Other
(0)
Ovary
(0)
Pancreas
(0)
Pancreatic
(0)
Parathyroid
(0)
Penile
(0)
Peripheral Blood
(0)
Peripheral Blood Mononuclear Cells
(0)
Peritoneal
(0)
Peritoneum
(0)
Pharynx
(0)
Pituitary
(0)
Pituitary Gland
(0)
Pituitary Tumor
(0)
Placenta
(0)
promyelocytic leukemia
(0)
Prostate
(0)
Prostate carcinoma
(0)
Renal
(0)
Reproductive
(0)
Reproductive System
(0)
Retina
(0)
Salivary Gland
(0)
Sciatic Nerve
(0)
Sertoli
(0)
Skeletal
(0)
Skeletal Muscle
(0)
Skin
(0)
Skin ; Keratinocytes
(0)
Small intestine
(0)
Smooth Muscle
(0)
Soft Tissue
(0)
Spinal
(0)
Spleen
(0)
Stem Cell
(0)
Stomach
(0)
Straitum
(0)
Sweat Gland
(0)
Tendon
(0)
Testes
(0)
Testis
(0)
Thymic
(0)
Thymus
(0)
Thyroid
(0)
Tongue
(0)
Tonsil
(0)
Trachea
(0)
Tumor
(0)
Umbilical Cord
(0)
Unknown
(0)
Urethra
(0)
Urinary Tract
(0)
Uterus
(0)
Uterus; endometrium
(0)
Vascular Endothelium
(0)
Ventral Mesencephalon
(0)
Vertebral Disc
(0)