Recombinant Human MCP-2 (CCL8) (E. coli)
Cat. No.
Z100635
Unit
Price
$89.00
Specifications
| Description | Monocyte chemotactic protein MCP-2 is a C-C chemokine. It shares over 60% amino acid identity with MCP-1 and MCP- 3 and has about 30% identity with other C-C chemokines MIP-1 alpha, RANTES, and MIP-1 beta. MCP-2 is chemotactic for and activates a wide variety of inflammatory cells, and its spectrum of action on leukocytes is similar to that of MCP-3, including monocytes, T lymphocytes, natural killer cells, basophils, mast cells, and eosinophils, but differs from MCP-1, which is not active on eosinophils. MCP-2 has been proposed to interact with multiple C-C chemokine receptors, including those used by MCP- 1 and MCP-3. However, since leukocytes express a multiplicity of chemokine receptors with promiscuous binding and functional properties, it is difficult to identify the receptors used by a given ligand on these cells. |
| SKU | Z100635 |
| Unit quantity | 25 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases |
Monocyte Chemotactic Protein-2, MCP2, HC14, C-C motif chemokine 8 Recombinant Human Monocyte Chemoattractant Protein-2 (CCL8) |
| Gene Symbol | CCL8 |
| Gene ID | 6355 |
| Accession Number | P80075 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 9 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered 20 mM solution in PBS |
| Function | The ED(50) was determined by the dose-dependent proliferation of Jurkat cells and was found to be <0.05ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
STR
There are no STR for this product yet!
FAQs
There are no FAQs for this product yet!
References
There are no references for this product yet!
Controls and Related Product:
Other Cell Lines
Select Species:
African Green Monkey (C. aethiops)
(0)
Bat
(0)
Bat (Chiroptera)
(0)
Bee
(0)
Bottlenose Dolphin (Tursiops)
(0)
Cabbage Looper (T. ni)
(0)
Cat (Feline)
(0)
Cattle
(0)
Chicken (Galline)
(0)
Chinese Hamster (C. griseus)
(0)
Cow (Bovine)
(0)
Deer (Cervidae)
(0)
Dog (Canine)
(0)
Duck (Anas)
(0)
Duck (Anatidae)
(0)
E. coli
(0)
European Sea Bass
(0)
European Sea Bass (D. labrax)
(0)
Fall Armyworm (S. frugiperda)
(0)
Fish
(0)
Fly (D. melanogaster)
(0)
Frog (Xenopus)
(0)
Fruit Fly (D. melanogaster)
(0)
Gilthead Sea Bream (S. aurata)
(0)
Goat (Capra)
(0)
Golden Hamster (M. auratus)
(0)
Goose (Anatidae)
(0)
Green Monkey (C. aethiops)
(0)
Green Monkey (C. sabaeus)
(0)
Hamster (M. auratus)
(0)
Horse (Equine)
(0)
Human
(0)
Human (H. sapiens)
(0)
Insect
(0)
Insect (Insecta)
(0)
Killifish (F. heteroclitus)
(0)
Luciola italica
(0)
Marmoset (Primate)
(0)
Mink
(0)
Mink (N. vison)
(0)
Monkey (Primate)
(0)
Moth (S. frugiperda)
(0)
Mouse
(0)
Mouse (M. musculus)
(0)
N/A
(0)
Other
(0)
Photinus pyralis
(0)
Pig (Porcine)
(0)
Quail (Coturnix)
(0)
Rabbit (Leporidae)
(0)
Rabbit (Leporine)
(0)
Rainbow Trout (O. mykiss)
(0)
Rat (R. norvegicus)
(0)
Rat (Rattus)
(0)
Renilla reniformis
(0)
Roundworm (C. elegans)
(0)
Rous Sarcoma Virus (RSV)
(0)
SARS-CoV-2
(0)
Sheep (Ovine)
(0)
Sheep (Ovis)
(0)
Turtle
(0)
Turtle (Testudines)
(0)
Universal
(0)
Zebrafish (D. rerio)
(0)
Select Tissue:
0
(0)
Achilles Tendon
(0)
Adipose
(0)
Adrenal Gland
(0)
Adrenal Glands
(0)
Airway
(0)
Airway/Lung
(0)
Amniotic Sac
(0)
Antimesometrial Decidua
(0)
Antler
(0)
Ascites
(0)
Auditory
(0)
Bee Cell
(0)
Bile Duct
(0)
Bladder
(0)
Blood
(0)
Blood (Immune)
(0)
Blood Vessel
(0)
Bone
(0)
Bone Marrow
(0)
Brain
(0)
Breast
(0)
CAF, Tumor
(0)
Caput Epididymis
(0)
Cartilage
(0)
Cerebrospinal Fluid
(0)
Cervix
(0)
Colon
(0)
Connective Tissue
(0)
Cord Blood
(0)
Digestive
(0)
Digestive System
(0)
Ear
(0)
Embryo
(0)
embryonic
(0)
Endometria
(0)
Endometrium
(0)
Esophagus
(0)
Eye
(0)
Fallopian Tube
(0)
Fibroblast
(0)
Gingiva
(0)
Hair
(0)
Hair Follicle
(0)
Head/Neck
(0)
Heart
(0)
HeLa
(0)
Hepatocellular Carcinoma
(0)
Hippocampus
(0)
Intestinal
(0)
Intestine
(0)
Kidney
(0)
Kidney, Cortex/Proximal tubule
(0)
Labial Salivary Gland
(0)
Larynx
(0)
Liver
(0)
Lung
(0)
Lung Carcinoma
(0)
Lung, bronchus
(0)
Lymph
(0)
Lymph node
(0)
Lymphatic System
(0)
lymphoblast
(0)
Malignant melanoma
(0)
Mammary
(0)
Mesencephalic Tissue
(0)
Mesentery
(0)
Microglia
(0)
Mouth/Oral
(0)
Muscle
(0)
Myoblast
(0)
Nasal Mucosa
(0)
Nerve
(0)
Nervous System
(0)
Oesophageal
(0)
Oesophagus
(0)
Oral
(0)
Organ of Corti
(0)
Other
(0)
Ovary
(0)
Pancreas
(0)
Pancreatic
(0)
Parathyroid
(0)
Penile
(0)
Peripheral Blood
(0)
Peripheral Blood Mononuclear Cells
(0)
Peritoneal
(0)
Peritoneum
(0)
Pharynx
(0)
Pituitary
(0)
Pituitary Gland
(0)
Pituitary Tumor
(0)
Placenta
(0)
promyelocytic leukemia
(0)
Prostate
(0)
Prostate carcinoma
(0)
Renal
(0)
Reproductive
(0)
Reproductive System
(0)
Retina
(0)
Salivary Gland
(0)
Sciatic Nerve
(0)
Sertoli
(0)
Skeletal
(0)
Skeletal Muscle
(0)
Skin
(0)
Skin ; Keratinocytes
(0)
Small intestine
(0)
Smooth Muscle
(0)
Soft Tissue
(0)
Spinal
(0)
Spleen
(0)
Stem Cell
(0)
Stomach
(0)
Straitum
(0)
Sweat Gland
(0)
Tendon
(0)
Testes
(0)
Testis
(0)
Thymic
(0)
Thymus
(0)
Thyroid
(0)
Tongue
(0)
Tonsil
(0)
Trachea
(0)
Tumor
(0)
Umbilical Cord
(0)
Unknown
(0)
Urethra
(0)
Urinary Tract
(0)
Uterus
(0)
Uterus; endometrium
(0)
Vascular Endothelium
(0)
Ventral Mesencephalon
(0)
Vertebral Disc
(0)