Recombinant Human IL37 (IL1F7) (E. coli)
Cat. No.
Z102085
Unit
Price
$163.00
Specifications
| Description | Member of the IL-1 family, IL-37 functions to curb excessive inflammation. In partnership with SMAD3, IL-37 suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Out of the five isoforms for IL-37 (a-e), this product represents isoform B that is expressed in testis, colon, placenta, lung and lymph node similar to isoform A and C but is the only one found in kidneys. |
| SKU | Z102085 |
| Unit quantity | 10 µg |
| Family | IL-1 Family |
| Aliases |
IL-37, IL-23, FIL1 zeta, IL-1X, Interleukin-1 family member 7, IL-1F7, Interleukin-1 homolog 4, IL-1H, IL-1H4, Interleukin-1 zeta, IL-1 zeta, Interleukin-1-related protein, IL-1RP1 Recombinant Human Interleukin-37/Interleukin-23 (IL37/IL23) |
| Gene Symbol | IL37 |
| Gene ID | 27178 |
| Accession Number | Q9NZH6 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 19.5 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS and DTT |
| Function | N.A. |
| Reconstitution | Reconstitute at 100 μg/mL in sterile PBS |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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African Green Monkey (C. aethiops)
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Bat
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Bat (Chiroptera)
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Bee
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Bottlenose Dolphin (Tursiops)
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Cabbage Looper (T. ni)
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Cat (Feline)
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Cattle
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Chicken (Galline)
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Chinese Hamster (C. griseus)
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Cow (Bovine)
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Deer (Cervidae)
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Dog (Canine)
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Duck (Anas)
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Duck (Anatidae)
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E. coli
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European Sea Bass
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European Sea Bass (D. labrax)
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Fall Armyworm (S. frugiperda)
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Fish
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Fly (D. melanogaster)
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Frog (Xenopus)
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Fruit Fly (D. melanogaster)
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Gilthead Sea Bream (S. aurata)
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Goat (Capra)
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Green Monkey (C. aethiops)
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Green Monkey (C. sabaeus)
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Human
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Human (H. sapiens)
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Insect (Insecta)
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Killifish (F. heteroclitus)
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Luciola italica
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Marmoset (Primate)
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Mink (N. vison)
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Monkey (Primate)
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Moth (S. frugiperda)
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Mouse
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Mouse (M. musculus)
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N/A
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Other
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Photinus pyralis
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Pig (Porcine)
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Quail (Coturnix)
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Rabbit (Leporine)
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Rat (R. norvegicus)
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Renilla reniformis
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Roundworm (C. elegans)
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Sheep (Ovine)
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Universal
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embryonic
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HeLa
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Intestinal
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Kidney, Cortex/Proximal tubule
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Labial Salivary Gland
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Larynx
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Liver
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Lung
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Lung Carcinoma
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Lung, bronchus
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Lymph
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Lymph node
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Lymphatic System
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lymphoblast
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Microglia
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Mouth/Oral
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Muscle
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Nasal Mucosa
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promyelocytic leukemia
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