Recombinant Human IL36RN (IL1F5) (E. coli)
Cat. No.
Z102645
Unit
Price
$89.00
Specifications
| Description | Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6. |
| SKU | Z102645 |
| Unit quantity | 20 µg |
| Family | IL-1 Family |
| Aliases | IL36RN FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, Interleukin-36 receptor antagonist protein |
| Gene Symbol | IL36RN |
| Gene ID | 26525 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and KCl |
| Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. This solution can then be diluted into other buffers. |
| Storage | This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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