Recombinant Human IL29 (IFNL1)
Cat. No.
Z100505
Unit
Price
$246.00
Specifications
| Description | The IFN-lambda gene family is composed of three distinct genes: IFN-lambda1 (IL-29), IFN-lambda2 (IL-28A), and IFN-lambda3 (IL-28B). IFN-lambda proteins exhibit only weak homology to IL-10, but, like IL-10, they also use the IL-10R2 chain as a component of their receptor complex. The IFN-receptor complex consists of the unique ligand-binding chain IFN- R. The IFN-lambda-1 gene is found exclusively in primate genomes and is 81% identical to IFN-lambda-2/3. IFN-lambda-s, which are now collectively referred to as type III IFNs, exhibit several features in common with type I IFNs, such as antiviral, antiproliferative, and antitumor activities. |
| SKU | Z100505 |
| Unit quantity | 20 µg |
| Family | IL-10/Interferon Family |
| Aliases |
Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, IL-29 Recombinant Human Interleukin-29 (IFNL1) |
| Gene Symbol | IFNL1 |
| Gene ID | 282618 |
| Accession Number | Q8IU54 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 20 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 µm filtered 20 mM PBS,130 mM NaCl solution pH 7.5 |
| Function | The ED(50) is determined in an anti-viral assay using human HepG2 cells infected with EMCV is typically 1-5 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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