Recombinant Human IL19 (E. coli)
Cat. No.
Z102445
Unit
Price
$126.00
Specifications
| Description | IL19 belongs to the IL-10 family of proinflammatory cytokines, which is composed of IL10, IL19, IL20, IL22, IL24, and IL26. IL19 is mainly expressed in monocytes and binds to the IL20 receptor complex which leads to the activation of the signal transducer and activator of transcription 3 (STAT3). It also performs up-regulation of IL6 and TNF-alpha and apoptosis induction, thus signifying its role in inflammatory responses. |
| SKU | Z102445 |
| Unit quantity | 10 µg |
| Family | IL-10/Interferon Family |
| Aliases | Melanoma differentiation-association protein-like protein, NG.1 |
| Gene Symbol | IL19 |
| Gene ID | 29949 |
| Accession Number | Q9UHD0 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 18 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 µm filtered solution in PBS |
| Function | The ED50 is 0.5-1.5 ng/mL as determined by a cell proliferation assay with the use of transfected BaF3 mouse pro-B cells with human IL-20Rα and human IL-20Rβ |
| Reconstitution | Reconstitute in sterile PBS at atleast 10µg/mL |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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