Recombinant Human FGF18 (E. coli)
Cat. No.
Z102315
Unit
Price
$89.00
Specifications
| Description | Human FGF18 is a member of the FGF family, a group of related proteins having broad mitogenic and cell survival activity. Members of this family have key roles in prenatal development, as well as postnatal growth and tissue regeneration. FGF18 promotes chondrogenesis, through interaction with FGFR3. It has been demonstrated to cause an increase in cartilage in a murine osteoarthritis model. It has also been implicated in the proliferation of tissues, notably the liver and small intestine. FGF18 also signals through FGFR 1c, 2c and 4. Recombinant Human FGF18 is a 20.4 kDa heparin binding growth factor. |
| SKU | Z102315 |
| Unit quantity | 20 µg |
| Family | FGF Family |
| Aliases | Fibroblast Growth Factor-18, zFGF5 |
| Gene Symbol | FGF18 |
| Gene ID | 8817 |
| Accession Number | O76093 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 20.4 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered solution in phosphate buffer, NaCl, KCl and EDTA (pH 7.5) |
| Function | The bioactivity was determined in a 3T3 cell proliferation assay. The ED50 was in the range of 0.05 - 0.1 ng/ml. |
| Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. Please note, filter sterilization is a must following reconstitution. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
STR
There are no STR for this product yet!
FAQs
There are no FAQs for this product yet!
References
There are no references for this product yet!
Controls and Related Product:
Other Cell Lines
Select Species:
African Green Monkey (C. aethiops)
(0)
Bat
(0)
Bat (Chiroptera)
(0)
Bee
(0)
Bottlenose Dolphin (Tursiops)
(0)
Cabbage Looper (T. ni)
(0)
Cat (Feline)
(0)
Cattle
(0)
Chicken (Galline)
(0)
Chinese Hamster (C. griseus)
(0)
Cow (Bovine)
(0)
Deer (Cervidae)
(0)
Dog (Canine)
(0)
Duck (Anas)
(0)
Duck (Anatidae)
(0)
E. coli
(0)
European Sea Bass
(0)
European Sea Bass (D. labrax)
(0)
Fall Armyworm (S. frugiperda)
(0)
Fish
(0)
Fly (D. melanogaster)
(0)
Frog (Xenopus)
(0)
Fruit Fly (D. melanogaster)
(0)
Gilthead Sea Bream (S. aurata)
(0)
Goat (Capra)
(0)
Golden Hamster (M. auratus)
(0)
Goose (Anatidae)
(0)
Green Monkey (C. aethiops)
(0)
Green Monkey (C. sabaeus)
(0)
Hamster (M. auratus)
(0)
Horse (Equine)
(0)
Human
(0)
Human (H. sapiens)
(0)
Insect
(0)
Insect (Insecta)
(0)
Killifish (F. heteroclitus)
(0)
Luciola italica
(0)
Marmoset (Primate)
(0)
Mink
(0)
Mink (N. vison)
(0)
Monkey (Primate)
(0)
Moth (S. frugiperda)
(0)
Mouse
(0)
Mouse (M. musculus)
(0)
N/A
(0)
Other
(0)
Photinus pyralis
(0)
Pig (Porcine)
(0)
Quail (Coturnix)
(0)
Rabbit (Leporidae)
(0)
Rabbit (Leporine)
(0)
Rainbow Trout (O. mykiss)
(0)
Rat (R. norvegicus)
(0)
Rat (Rattus)
(0)
Renilla reniformis
(0)
Roundworm (C. elegans)
(0)
Rous Sarcoma Virus (RSV)
(0)
SARS-CoV-2
(0)
Sheep (Ovine)
(0)
Sheep (Ovis)
(0)
Turtle
(0)
Turtle (Testudines)
(0)
Universal
(0)
Zebrafish (D. rerio)
(0)
Select Tissue:
0
(0)
Achilles Tendon
(0)
Adipose
(0)
Adrenal Gland
(0)
Adrenal Glands
(0)
Airway
(0)
Airway/Lung
(0)
Amniotic Sac
(0)
Antimesometrial Decidua
(0)
Antler
(0)
Ascites
(0)
Auditory
(0)
Bee Cell
(0)
Bile Duct
(0)
Bladder
(0)
Blood
(0)
Blood (Immune)
(0)
Blood Vessel
(0)
Bone
(0)
Bone Marrow
(0)
Brain
(0)
Breast
(0)
CAF, Tumor
(0)
Caput Epididymis
(0)
Cartilage
(0)
Cerebrospinal Fluid
(0)
Cervix
(0)
Colon
(0)
Connective Tissue
(0)
Cord Blood
(0)
Digestive
(0)
Digestive System
(0)
Ear
(0)
Embryo
(0)
embryonic
(0)
Endometria
(0)
Endometrium
(0)
Esophagus
(0)
Eye
(0)
Fallopian Tube
(0)
Fibroblast
(0)
Gingiva
(0)
Hair
(0)
Hair Follicle
(0)
Head/Neck
(0)
Heart
(0)
HeLa
(0)
Hepatocellular Carcinoma
(0)
Hippocampus
(0)
Intestinal
(0)
Intestine
(0)
Kidney
(0)
Kidney, Cortex/Proximal tubule
(0)
Labial Salivary Gland
(0)
Larynx
(0)
Liver
(0)
Lung
(0)
Lung Carcinoma
(0)
Lung, bronchus
(0)
Lymph
(0)
Lymph node
(0)
Lymphatic System
(0)
lymphoblast
(0)
Malignant melanoma
(0)
Mammary
(0)
Mesencephalic Tissue
(0)
Mesentery
(0)
Microglia
(0)
Mouth/Oral
(0)
Muscle
(0)
Myoblast
(0)
Nasal Mucosa
(0)
Nerve
(0)
Nervous System
(0)
Oesophageal
(0)
Oesophagus
(0)
Oral
(0)
Organ of Corti
(0)
Other
(0)
Ovary
(0)
Pancreas
(0)
Pancreatic
(0)
Parathyroid
(0)
Penile
(0)
Peripheral Blood
(0)
Peripheral Blood Mononuclear Cells
(0)
Peritoneal
(0)
Peritoneum
(0)
Pharynx
(0)
Pituitary
(0)
Pituitary Gland
(0)
Pituitary Tumor
(0)
Placenta
(0)
promyelocytic leukemia
(0)
Prostate
(0)
Prostate carcinoma
(0)
Renal
(0)
Reproductive
(0)
Reproductive System
(0)
Retina
(0)
Salivary Gland
(0)
Sciatic Nerve
(0)
Sertoli
(0)
Skeletal
(0)
Skeletal Muscle
(0)
Skin
(0)
Skin ; Keratinocytes
(0)
Small intestine
(0)
Smooth Muscle
(0)
Soft Tissue
(0)
Spinal
(0)
Spleen
(0)
Stem Cell
(0)
Stomach
(0)
Straitum
(0)
Sweat Gland
(0)
Tendon
(0)
Testes
(0)
Testis
(0)
Thymic
(0)
Thymus
(0)
Thyroid
(0)
Tongue
(0)
Tonsil
(0)
Trachea
(0)
Tumor
(0)
Umbilical Cord
(0)
Unknown
(0)
Urethra
(0)
Urinary Tract
(0)
Uterus
(0)
Uterus; endometrium
(0)
Vascular Endothelium
(0)
Ventral Mesencephalon
(0)
Vertebral Disc
(0)