Recombinant Human Eotaxin (CCL11) (E. coli)
Cat. No.
Z100175
Unit
Price
$89.00
Specifications
| Description | Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils. |
| SKU | Z100175 |
| Unit quantity | 20 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases | SCYA11, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11 |
| Gene Symbol | CCL11 |
| Gene ID | 6356 |
| Accession Number | P51671 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8.5 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from as 0.2 μm filtered solution in PBS (pH 7.5) |
| Function | Activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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