Recombinant Human CXCL16 (E. coli)
Cat. No.
Z102385
Unit
25 µg
Price
$205.00
Specifications
| Description |
Chemokine (CXC motif) ligand 16, is a small cytokine belonging to the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 is composed of its typical CXC chemokine domain, a mucin-like stalk, a transmembrane domain, and a cytoplasmic tail which allow CXCL16 to act as a cell surface bound molecule as well as a soluble chemokine. Human CXCL16 shares 70% amino acid sequence similarity with the mouse and CXCL16 expression is induced by IFN-γ and TNF-α. CXCL16 is produced by dendritic cells in lymphoid organs, and by red pulp spleen cells. The expression of CXCL16 may attract lymphocytes during inflammation and assist some immune responses. |
| SKU | Z102385 |
| Unit quantity | 25 µg |
| Family | Chemokine-alpha Family (CXC) |
| Aliases | Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16, transmembrane chemokine CXCL16 |
| Gene Symbol | CXCL16 |
| Gene ID | 58191 |
| Accession Number | Q9H2A7 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 10.4 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 µm filtered solution in PBS |
| Function | The ED50 is 2.5-12 ng/mL as determined by its ability to chemoattract activated lymphocytes (at a concentration of 100.0 ng/mL) |
| Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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