Recombinant Human CCL22 (E. coli)
Cat. No.
Z101015
Unit
Price
$184.00
Specifications
| Description | CCL22 (monocyte-derived chemokine) was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells . One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Similarly, a presumed role for CCR4+ cells has been suggested for endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes |
| SKU | Z101015 |
| Unit quantity | 20 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases |
STCP-1, ABCD-1, CCL22, CC chemokine STCP-1, MDC(1-69), SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1, MDC, C-C motif chemokine 22 Recombinant Human Macrophage-Derived Chemokine (CCL22) |
| Gene Symbol | CCL22 |
| Gene ID | 6367 |
| Accession Number | O00626 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from 0.2 μm filtered solution in Tris and NaCl, pH 7.0. |
| Function | The ED(50) was determined by the dose-dependent proliferation of MGC823 cells and was found to be <5ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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