Recombinant Human 4-1BB Receptor (TNFRSF9) (E. coli)
Cat. No.
Z101085
Unit
Price
$89.00
Specifications
| Description | 4-1BB Receptor (CD137) is a member of the TNF receptor superfamily expressed on activated CD4 and CD8 T cells as well as on activated natural killer cells. The binding of 4-1BB Receptor to its TNF family ligand, 4-1BB ligand (4-1BBL) delivers a co-stimulatory signal to resting T cells leading to high level IL2 production independently of CD28 signaling. Recombinant Human 4-1BB Receptor represents the soluble, cysteine-rich TNFR-like extracellular domain of 4-1BB Receptor. |
| SKU | Z101085 |
| Unit quantity | 20 µg |
| Family | Other Growth Factors/Cytokines |
| Aliases |
Tumor necrosis factor receptor superfamily member 9, 41BB, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137 Recombinant Human 4-1BB (TNFRSF9) |
| Gene Symbol | TNFRSF9 |
| Gene ID | 3604 |
| Accession Number | Q07011 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 18 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Lyophilized from 0.2 μm filtered solution in PBS (pH 7.5) |
| Function | The ED50 as determined by dose dependent proliferation of human megakaryocytic leukemia cell line is <0.5ng/ml. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | Recombinant 4-1BB Receptor can be stored in working aliquots at 2° - 8°C for one month, or at -20°C to -70°C for twelve months. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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