CHIR99021
Specifications
Cat. No. | G611 |
Name | CHIR99021 |
Price | $63.00 |
Unit | 2.0 mg |
Category | Reagents and Chemicals |
Description |
Formula Name
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile
Formula
C22H18Cl2N8
Molecular Weight
465 g/mol
Stability
2 years
QC
MR and Mass Spectrometry
Function
Glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo.
Small Molecule Action
Reprogramming
|
Concentration | 10mM in DMSO (~430ul) |
Purity | 99% |
Storage Condition |
-20°C |
Caution | For Research Use Only, not for therapeutic or diagnostic purposes. |
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References
- Shen, J., Lyu, C., Zhu, Y., Feng, Z., Zhang, S., Hoyle, D. L., … Wang, Z. Z. "Defining early hematopoietic‐fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, activin, and BMP signaling" Journal of Cellular Physiology 234(9):16136–16147 (2019). DOI: 10.1002/jcp.28272.