Anti-STAT6 (Ab-645) Antibody
Cat. No.
Y021051
Unit
100 μg
Price
$299.00
Specifications
| Cat. No. | Y021051 |
| Name | Anti-STAT6 (Ab-645) Antibody |
| Clone | N/A |
| Price | $299.00 |
| Unit | 100 μg |
| Category | Polyclonal Antibodies |
| Gene Name | STAT6 |
| Alias | D12S1644, IL-4-STAT |
| Application | WB,IHC |
| Application Info | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human STAT6 around the phosphorylation site of threonine 645 (P-A-TP-I-K). |
| Concentration | 1ug/ul |
| Recommended Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | STAT6 (Ab-645) antibody detects endogenous levels of total STAT6 protein. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Caution | This product is distributed for laboratory research only. Not for diagnostic use. |
| Guarantee | abm guarantees that all our Anti-STAT6 (Ab-645) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SAB Y02 |
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