Anti-SCD1 (Mouse Monoclonal) Antibody
Cat. No.
G076
Unit
100 μg
Price
$225.00
Specifications
| Cat. No. | G076 |
| Name | Anti-SCD1 (Mouse Monoclonal) Antibody |
| Clone | CD.E10 |
| Price | $225.00 |
| Unit | 100 μg |
| Category | Monoclonal Antibodies |
| Application | WB,IHC,ELISA,IP |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human,Mouse |
| Immunogen | Full length recombinant protein. |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Western blot, ELISA, IP, and IHC in obesity research. Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The SCD1 gene is tightly regulated by signals such as insulin, leptin, carbohydrate, fatty acids and temperature. The enzyme (mouse 355aa, rat 358aa; ~37 KDa) is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. The SCD-1 expression is higher in female than male mouse. The repression of RNA levels and enzyme activity of hepatic SCD-1 by Leptin has been shown to significantly reduce the triglyceride storage, VLDL production and therefore an increase in fatty acid oxidation. Inhibition of SCD-1 could be of benefit for treatment of obesity, hepatic steatosis and other metabolic disorders. |
| Storage Buffer | PBS, pH 7.4 with 0.05% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Specificity | Reacts with human and mouse proteins. |
| Guarantee | abm guarantees that all our Anti-SCD1 (Mouse Monoclonal) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | Epitope |
Protocols
There are no Protocols for this product yet!
Documents
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FAQs
| I have different band sizes for SCD1 on my western blot. Why? | |
|
SCD1 undergoes different modifications post-translationally in different cell types, so this will affect the migration speed and the final molecular size of SCD1.
|
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