Anti-Myc (Phospho-Ser62) Antibody
Specifications
Cat. No. | Y011311 |
Name | Anti-Myc (Phospho-Ser62) Antibody |
Clone | Polyclonal |
Price | $299.00 |
Unit | 100 μg |
Category | Polyclonal Antibodies |
Gene Name | Myc |
Alias | c-Myc, bHLHe39 |
Application | ICC/IF |
Application Info | IF:1:100~1:200 |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse,Rat |
Description | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] |
Immunogen | The antibody was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of serine 62(P-L-SP-P-S). |
Isotype | IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | IF:1:100~1:200 |
Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse,Rat |
Specificity | Myc (Phospho-Ser62) Antibody detects endogenous levels of Myc only when phosphorylated at serine 62. |
Purity | Affinity purified |
Guarantee | abm guarantees that all our Anti-Myc (Phospho-Ser62) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SAB Y01 |
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