Anti-MDM2 (phospho-Ser166) Antibody
Cat. No.
Y011550
Unit
100 μg
Price
$299.00
Specifications
| Cat. No. | Y011550 |
| Name | Anti-MDM2 (phospho-Ser166) Antibody |
| Clone | Polyclonal |
| Price | $299.00 |
| Unit | 100 μg |
| Category | Polyclonal Antibodies |
| Gene Name | MDM2 |
| Alias | HDM2, HDMX, MGC5370 |
| Application | WB,IHC,IP |
| Application Info | WB:1:500~1:1000 IHC:1:50~1:100 IF:1:100~1:200 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013] |
| Immunogen | The antibody was produced against synthesized phosphopeptide derived from human MDM2 around the phosphorylation site of Serine 166 (A-I-SP-E-T). |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | WB:1:500~1:1000 IHC:1:50~1:100 IF:1:100~1:200 |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | MDM2 (phospho-Ser166) Antibody detects endogenous levels of MDM2 only when phosphorylated at Serine 166. |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-MDM2 (phospho-Ser166) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SAB Y01 |
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