Anti-MAD2(L1) Antibody
Cat. No.
Y120003
Unit
100 μg
Price
$267.00
Specifications
| Cat. No. | Y120003 |
| Name | Anti-MAD2(L1) Antibody |
| Clone | KD6.17D10.2G9 |
| Price | $267.00 |
| Unit | 100 μg |
| Category | Monoclonal Antibodies |
| Gene Name | MAD2L1 |
| Alias | MAD2, HSMAD2 |
| Application | WB,IP |
| Application Info | Titrate for optimal dilution for your application. |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description | Mad2 provides feedback control that prevents cells with incompletely assembled spindles from leaving mitosis. Researchers have found that deletion of a single Mad2 allele results in a defective mitotic checkpoint; Mad2+/- mice develop lung tumors at high rates after long latencies, implicating defects in the mitotic checkpoint of tumorigenesis . Mad2 is an important target in cancer research because it may sensitize cells to existing chemotherapeutics and its expression may be an indicator of cellular sensitivity to chemotherapy. |
| Immunogen | Recombinant human Mad2 |
| Isotype | IgG1 |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Titrate for optimal dilution for your application. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | Western blot with a variety of human cell lines confirms that the antibody is specific for human Mad2; other species specificity has not yet been determined. |
| Purity | Purified ascites. |
| Guarantee | abm guarantees that all our Anti-MAD2(L1) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | FCCC |
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