Anti-Lck (Phospho-Tyr505) Antibody
Cat. No.
Y011537
Unit
100 μg
Price
$299.00
Specifications
| Cat. No. | Y011537 |
| Name | Anti-Lck (Phospho-Tyr505) Antibody |
| Clone | Polyclonal |
| Price | $299.00 |
| Unit | 100 μg |
| Category | Polyclonal Antibodies |
| Gene Name | Lck |
| Application | WB |
| Application Info | WB: 1:500~1:1000 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008] |
| Immunogen | The antibody was produced against synthesized phosphopeptide derived from human Lck around the phosphorylation site of tyrosine 505 (G-Q-YP-Q-P). |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | WB: 1:500~1:1000 |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | Lck (phospho-Tyr505) antibody detects endogenous levels of Lck only when phosphorylated at tyrosine 505. |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-Lck (Phospho-Tyr505) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SAB Y01 |
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