Anti-Human CD133(Prominin-1) Antibody
Cat. No.
G107
Unit
100 μg
Price
$225.00
Specifications
| Cat. No. | G107 |
| Name | Anti-Human CD133(Prominin-1) Antibody |
| Clone | Monoclonal |
| Price | $225.00 |
| Unit | 100 μg |
| Category | Monoclonal Antibodies |
| Application | WB |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description | The EMK08 monoclonal antibody reacts with human CD133 (Prominin-1), a 120 kDa member of the pentaspan family of proteins, which also includes Prominin-2. Their expression is found within plasma membrane protrusions such as epithelial microvilli. CD133 can exist in a number of alternatively spliced isoforms, and the protein has several N-linked glycosylation sites; the occurrence of both may be tissue-dependent. Human CD133 was first identified as an epitope expressed on CD34+ hematopoietic progenitors. Although the ligand and function of CD133 remain unknown, it has since proven to be very useful as a marker for both stem cells and cancer stem cells. In addition to its expression on hematopoietic precursors, CD133 has been used to identify tumorigenic colon cancer stem cells, brain cancer stem cells, prostate cancer stem cells, in addition to others. |
| Immunogen | Affinity purified |
| Isotype | IgG2b, k |
| Concentration | 100ug/100ul |
| Storage Buffer | PBS, pH 7.4 with less than or equal to 0.09% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-Human CD133(Prominin-1) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | ABM |
Protocols
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Documents
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FAQs
| Why is the molecular weight around 130kDa when the predicted weight is only 97kDa? | |
|
Due to heavy glycosylation, CD133's apparent molecular weight is 130 kDa.
|
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