Anti-HDAC4 (Phospho-Ser632) Antibody
Specifications
Cat. No. | Y011192 |
Name | Anti-HDAC4 (Phospho-Ser632) Antibody |
Clone | N/A |
Price | $299.00 |
Unit | 100 μg |
Category | Polyclonal Antibodies |
Gene Name | HDAC4 |
Alias | KIAA0288, HDAC-A, HDACA, HD4, HA6116 |
Application | WB |
Application Info | WB: 1:500~1:1000 |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse,Rat |
Description | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |
Immunogen | The antiserum was produced against synthesized phosphopeptide derived from human HDAC4 around the phosphorylation site of serine 632 (A-Q-SP-S-P). |
Concentration | 1ug/ul |
Recommended Dilutions | WB: 1:500~1:1000 |
Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse,Rat |
Specificity | HDAC4 (phospho-Ser632) antibody detects endogenous levels of HDAC4 only when phosphorylated at serine 632. |
Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. |
Guarantee | abm guarantees that all our Anti-HDAC4 (Phospho-Ser632) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SAB Y01 |
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