Anti-hBUB1 Antibody
Cat. No.
Y120001
Unit
100 μg
Price
$205.00
Specifications
| Cat. No. | Y120001 |
| Name | Anti-hBUB1 Antibody |
| Clone | P8.14H5.1H1 |
| Price | $205.00 |
| Unit | 100 μg |
| Category | Monoclonal Antibodies |
| Gene Name | BUB1 |
| Alias | hBUB1, BUB1A |
| Application | WB,IP,ICC/IF |
| Application Info | Titrate for optimal dilution for your application. |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description | The BUB family of serine/threonine kinases is a major target of oncology therapeutic research and development. hBUB1 and hBUBR1 are kinases that associate with hBUB3 and are essential components of the mitotic checkpoint. hBUBR1 appears to provide two checkpoint functions by monitoring CENP-E-dependent activities at the kinetochore and by regulating cyclosome/APC activity.hBUBR1 is required in order for microtubule inhibitors to arrest cells in mitosis. Non-mutational inactivation of hBUB1 and hBUBR1 appear related to stage of colon cancer and could be related to aneuploidy in human colorectal and other cancers. |
| Immunogen | Purified ascites. |
| Isotype | IgG1 |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Titrate for optimal dilution for your application. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Purity | Purified ascites. |
| Guarantee | abm guarantees that all our Anti-hBUB1 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | ABM |
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