Anti-CDK6 (phospho-Tyr24) Antibody
Cat. No.
Y011543
Unit
100 μg
Price
$299.00
Specifications
| Cat. No. | Y011543 |
| Name | Anti-CDK6 (phospho-Tyr24) Antibody |
| Clone | Polyclonal |
| Price | $299.00 |
| Unit | 100 μg |
| Category | Polyclonal Antibodies |
| Gene Name | Cdk6 |
| Alias | PLSTIRE |
| Application | IHC,ICC/IF |
| Application Info | IHC: 1:50~100 IF:1:100~1:200 |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse |
| Description | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009] |
| Immunogen | The antibody was produced against synthesized phosphopeptide derived from human CDK6 around the phosphorylation site of tyrosine 24 (G-A-YP-G-K). |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | IHC: 1:50~100 IF:1:100~1:200 |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse |
| Specificity | CDK6 (phospho-Tyr24) Antibody detects endogenous levels of CDK6 only when phosphorylated at tyrosine 24. |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-CDK6 (phospho-Tyr24) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SAB Y01 |
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