Anti-ABL1/2 (phospho-Tyr393/429) Antibody
Specifications
Cat. No. | Y011530 |
Name | Anti-ABL1/2 (phospho-Tyr393/429) Antibody |
Clone | Polyclonal |
Price | $299.00 |
Unit | 100 μg |
Category | Polyclonal Antibodies |
Gene Name | ABL2 |
Alias | ARG |
Application | IHC,ICC/IF |
Application Info | IHC: 1:50~100 IF:1:100~1:200 |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse |
Description | This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009] |
Immunogen | The antibody was produced against synthesized phosphopeptide derived from human ABL1/2 around the phosphorylation site of tyrosine 393/429 (D-T-YP-T-A). |
Isotype | IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | IHC: 1:50~100 IF:1:100~1:200 |
Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse |
Specificity | ABL1/2 (phospho-Tyr393/429) Antibody detects endogenous levels of ABL1/2 only when phosphorylated at tyrosine393/429. |
Purity | Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Guarantee | abm guarantees that all our Anti-ABL1/2 (phospho-Tyr393/429) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SAB Y01 |
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