CRISPR Knockout Adenovirus Library

abm's CRISPR Knockout sgRNA Adenoviruses offer high infection efficiency and level of sgRNA expression in a broad range of cells. Adenovirus is non-integrating, so there is less risk of interfering with host gene expression. We offer a collection of Knockout Adenoviruses that express sgRNAs targeting any human, mouse, or rat gene.

Key Features

Collection of sgRNAs for knockout of your gene of interest. Human, mouse, and rat gene targets are available.
Adenoviral delivery for high level expression without integration into the host genome.

For multiplex gRNA expression from lentiviral vector, use our Custom Multiplex gRNA Service.
For knockout of up to 100 target genes, take advantage of our pooled Custom Targeted Lentiviral sgRNA Library Service.

Popular Products

Additional Resources on CRISPR Technology

Search Knockout sgRNA Library

Knockout sgRNA Library

We offer sgRNA adenoviruses for knockout of any human, mouse, or rat gene.

Product Information

Performance/Data
Click to see our CRISPR Knockout Case Study, including experimental design and supporting data.
Workflow
Basic workflow for transduction of abm's sgRNA adenovirus.
Need Help Getting Started?
This handbook outlines guidelines for CRISPR sgRNA design and the experimental procedures needed to achieve a specific gene knockout.

Documents

Top Publications

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Kang, Y J et al.
Nat. Commun. 6:8371 (2015).

DOI: 10.1038/ncomms9371.

Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET.

Shirasaki, T. et al.
Nature Communications. (2022).

doi: 10.1038/s41467-022-30879-3

Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.

Okugawa, Y et al.
Gut (2015)

doi:10.1136/gutjnl-2015-309359